The NLISIS Meltfit One is a new, reliable and efficient method for coupling capillary columns in GC, GCxGC, CZE and all other coupled-column capillary separation techniques.

In five simple steps the NLISIS Meltfit One establishes an automated and standardised connection between two capillary columns, using a deactivated Meltfit Tube. A combination of heat and air pressure fixates the columns in the tube, establishing a seamless connection. The Meltfit has been tested with up to eleven connections in series, without showing any noticeable band-broadening or leakage.

Using the NLISIS Meltfit One, coupling capillary columns becomes simple, stable, secure and swift, resulting in more successful and reliable analyses and lower costs of ownership. In addition, the Meltfit One will help organisations align internal operating procedures and meet regulatory requirements

Column to column connection to connect columns with different stationary phases for improved selectivity, to make a longer column or to mend a broken column

Guard column / retention gap to column to protect the analytical column from dirt and to allow on-column injections onto 329 or 250 µm columns

GCxGC to fit the various connectors in the tiny modulator space or small second dimension oven.

GC-MS to avoid having to vent the MS every time a new column needs to be installed (if a narrow transfer capillary is used) or to avoid careful repositioning of the column in the ion source with every column replacement.

In LC some initial, very successful tests vave been done. We hope to make the Meltfit technology available to LC users in the course of 2008